Operating machinery by the power of thought alone —— what sounds like technology out of a science fiction novel is starting to become a real possibility. Brain —— machine interface (BMI) is a technology that aims to make up for deficiencies in human neural function through the direct exchange of signals between the brain and a machine. Regarded as being particularly effective in promoting social engagement by patients with spinal cord injuries or amyotrophic lateral sclerosis (ALS), BMI could, in the future, potentially be combined with artificial intelligence (AI) and engineering technology to enable people to operate electric wheelchairs, powered exoskeletons, smart devices, home appliances, and all kinds of other devices by the power of thought alone.