MEDICINE Special Feature 1 – The Evolution in Visualization A new imaging system visualizing the pathogenesis of arthritis Produced by infected tissue, chemokines induce the migration of immune cells in the blood to the site of the infection, where the cells engulf the bacteria (a process called phagocytosis), bringing down the inflammation. However, if they continue to migrate, they can also attack healthy organs, triggering rheumatoid arthritis or other autoimmune diseases. Scientists had identified that the migration of immune cells due to chemokines was involved in autoimmune disease, but the details remained a mystery. However, the development of a new imaging system capable of visualizing immune cell and chemotactic factor dynamics and analyzing them in real time has brought to light the mechanisms involved.